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Echinobase

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ECB-ANTIBODY-26396488

Antibody Name: phospho-LOC576066 Ab1

Common Name: phosphorylated dual specificity mitogen-activated protein kinase kinase 1

RRID:
Synonyms: dual phosphorylated MAPK kinase, phospho-MEK (Ser217/221)

Antigens
Gene: LOC576066

Clone Type: Polyclonal
Source: New England Biolabs

Antibody
Clone Number
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Echinoderm Reactivity S. purpuratus, L. pictus
Non-Echinoderm Reactivity chicken, monkey, mouse, rat, yeast
Description: Antibody to an active, dual-phosphorylated form of a ~45-kDa enzyme in sea urchin eggs. Supplied by New England Biolabs and Cell Signaling Technology (#9121).
Immunogen
Name Human MEK1/2 (Ser217/221)
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Proprietary sequence corresponding to residues surrounding dual phosphorylation site. UniProt ID #s: P36507 , Q02750.
Sequence
Reported Usage
western blot
Publications
???displayAntibody.papersFirst??? Calcium-mediated inactivation of the MAP kinase pathway in sea urchin eggs at fertilization., Dev Biol 2001  
???displayAntibody.papersRecent??? A MAPK pathway is involved in the control of mitosis after fertilization of the sea urchin egg., Dev Biol 2005  
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