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Antibody Name: p160 Ab2 Common Name: cell surface protein p160 RRID: Synonyms: p160 Antigens Gene: p160 Clone Type: Polyclonal Source:

Antibody
Clone Number
Purification	Affinity Purification
Isotype	IgG
Host Organism	rabbit
Echinoderm Reactivity	S. purpuratus
Non-Echinoderm Reactivity
Description:	Function-blocking antibody that reacts with an ~85-kDa fragment, 60-kDa doublet, and 30-kDa doublet corresponding to an integral plasma membrane protein that has been demonstrated to prevent detachment and proper formation of the fertilization envelope. Generated by Sigma-Genosys, The Woodlands, TX for usage by the Wessel lab (Brown University, Providence, RI).
Immunogen
Name	pan p160
Type	polypeptide
Post Translational Modifications	None
Source Organism	purple sea urchin
Description	Three bacterially expressed recombinant protein fragments encompassing the majority of the protein (amino acid residues 188-1447) that were each fused to N-terminal Histidine tags. Consists of Segment A (1st CUB motif), Segment B (2nd and 3rd CUB motifs), and Segment C (4th and 5th CUB motifs and transmembrane domain).
Sequence
Reported Usage
immunofluorescence
immunoprecipitation
western blot
Publications
???displayAntibody.papersFirst???	Proteolytic cleavage of the cell surface protein p160 is required for detachment of the fertilization envelope in the sea urchin., Dev Biol 2004
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