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Antibody Name: LOC590790 Ab2 Common Name: mucin-17 RRID: Synonyms: 183, Hyalin, Tg-HYL Antigens Gene: LOC590790 Clone Type: Monoclonal Source:

Antibody
Clone Number	183
Purification	Immunoglobulin Fractionation
Isotype	IgG1
Host Organism	mouse
Echinoderm Reactivity	S. purpuratus, L. pictus
Non-Echinoderm Reactivity
Description:	Function-blocking antibody that arrests gastrulation in various sea urchin species (Lytechinus variegatus, Tripneustes gratilla, Colobocentrotus aratus, Arbacia punctulata) by perturbing cell-hyaline layer adhesions. Antibody created by D. L. Adelson and T. Humphreys at the University of Hawaii monoclonal antibody facility. Previously provided by the McClay lab (Duke University), Wessel lab (Brown University), and Humphrey lab (University of Hawaii-Manoa, Kewalo Marine Institute).
Immunogen
Name	Whole Pluteus-Stage Embryos
Type	homogenized tissue
Post Translational Modifications	unknown post translational modifications
Source Organism	Echinoderms
Description	Tripneustes gratilla embryos sonicated and lysed using distilled water.
Sequence
Reported Usage
immunofluorescence
immunohistochemistry
immunoprecipitation
western blot
Publications
???displayAntibody.papersFirst???	Cell polarity in sea urchin embryos: reorientation of cells occurs quickly in aggregates., Dev Biol 1988
???displayAntibody.papersRecent???	Cell rearrangement induced by filopodial tension accounts for the late phase of convergent extension in the sea urchin archenteron., Mol Biol Cell 2019
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