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ECB-ANTIBODY-26396151
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Antibody Name:
msp130 Ab4
Common Name: mesenchyme-specific cell surface glycoprotein RRID: Synonyms: 1223, 130-kDa primary mesenchyme cell-specific glycoprotein, mesenchyme-specific protein 130
Source: |
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| Antibody | |
| Clone Number | 1223 |
| Purification | Affinity Purification |
| Isotype | IgG1 |
| Host Organism | mouse |
| Echinoderm Reactivity | S. purpuratus, L. pictus |
| Non-Echinoderm Reactivity | |
| Description: | Function-blocking antibody demonstrated to inhibit spiculogenesis of the sea urchin larval skeleton by reacting with a carbohydrate epitope and preventing calcium deposition by the primary mesenchyme cells in vivo. Created and previously supplied by the laboratory of Dr. William Lennarz (formerly M. D. Anderson Hospital and Tumor Institute, Houston, Texas). |
| Immunogen | |
| Name | Gastrula-Stage Embryonic Cell Suspension |
| Type | other immunogen type |
| Post Translational Modifications | Glycosylation |
| Source Organism | purple sea urchin |
| Description | 1-10^6 cells obtained by filtering glycoprotein-containing cells from dissociated mesenchyme blastula stage (20-21 hpf) embryos. |
| Sequence | |
| Reported Usage | |
| immunofluorescence | |
| immunoprecipitation | |
| western blot | |
| Publications | |
| ???displayAntibody.papersFirst??? |
A monoclonal antibody inhibits calcium accumulation and skeleton formation in cultured embryonic cells of the sea urchin., Cell 1985 |
| ???displayAntibody.papersRecent??? |
A method of microinjection: delivering monoclonal antibody 1223 into sea urchin embryos., Mol Cells 1999 |
| ???displayAntibody.papersAll??? | |