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Antibody Name: LOC590586 Ab7 Common Name: detyrosinated tubulin alpha-1A chain RRID: Synonyms: detyrosinated alpha-tubulin, detyrosylated alpha-tubulin, Glu-tubulin, L3 Antigens Gene: LOC590586 Clone Type: Polyclonal Source:

Antibody
Clone Number
Purification	Immunoglobulin Fractionation
Isotype	IgG
Host Organism	rabbit
Echinoderm Reactivity	S. purpuratus, P. lividus,
Non-Echinoderm Reactivity	Lytechinus pictus, mouse, rat
Description:	Antibody that specifically binds to a detyrosinated form of alpha-tubulin that terminates at a glutamic acid residue in sea urchin sperm axonemes. Created by G. G. Gundersen, M. H. Kalnoski, and J C Bulinski at the University of California in Los Angeles (PMID: 6386177). Also reacts with Arbacia lixula.
Immunogen
Name	Glu peptide
Type	synthetic sequence
Post Translational Modifications	Proteolysis
Source Organism	human
Description	Replica of the carboxy-terminal seven amino acid residues of mammalian Glu-tubulin that terminates at Glu450 conjugated to keyhole limpet hemocyanin (KLH).
Sequence	[+] GEEEGEE
Reported Usage
immunohistochemistry
Publications
???displayAntibody.papersFirst???	The polyglutamylated lateral chain of alpha-tubulin plays a key role in flagellar motility., J Cell Sci 1996
???displayAntibody.papersRecent???	Composition and organization of tubulin isoforms reveals a variety of axonemal models., Biol Cell 1999
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