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Antibody Name: pkd1l2a Ab3 Common Name: polycystin 1 like 2 (gene/pseudogene) A RRID: Synonyms: 210-kDa sperm surface glycoprotein, J18/2, sperm receptor for egg jelly Antigens Gene: pkd1l2a Clone Type: Monoclonal Source:

Antibody
Clone Number	J18/2
Purification
Isotype	IgG3
Host Organism	mouse
Echinoderm Reactivity	S. purpuratus
Non-Echinoderm Reactivity
Description:	Spermatazoa-specific antibody that has been demonstrated to prevent the calcium release that is initiated by the acrosome reaction. Created and previously supplied by Dr. J. S. Trimmer & V. D. Vacquier (Scripps Institution of Oceanography, University of California, San Diego).
Immunogen
Name	Sperm Membrane Vesicle Protein
Type	polypeptide
Post Translational Modifications	None
Source Organism	purple sea urchin
Description	Receptor protein band purified from sperm membrane vesicles using SDS-Page.
Sequence
Reported Usage
enzyme-linked immunosorbent assay
immunofluorescence
immunohistochemistry
immunoprecipitation
western blot
Publications
???displayAntibody.papersFirst???	Monoclonal antibodies increase intracellular Ca2+ in sea urchin spermatozoa., Proc Natl Acad Sci U S A 1986
???displayAntibody.papersRecent???	Seasonal changes in testicular structure and localization of a sperm surface glycoprotein during spermatogenesis in sea urchins., J Histochem Cytochem 1993
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