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Echinobase

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ECB-ANTIBODY-26395655

Antibody Name: phospho-mapk1 Ab5

Common Name: phosphorylated mitogen-activated protein kinase 1

RRID:
Synonyms: MAPK-YT, diphosphorylated ERK1/2, phosphorylated extracellular signal-regulated kinase 1/2

Antigens
Gene: mapk1

Clone Type: Monoclonal
Source: Sigma-Aldrich

Antibody
Clone Number MAPK-YT
Purification Ascites
Isotype IgG1
Host Organism mouse
Echinoderm Reactivity S. purpuratus, P. lividus
Non-Echinoderm Reactivity cow, fruitfly, human, mouse, rat, worm, yeast
Description: Specifically reacts with the activated form of the enzyme. Supplied by Sigma-Aldrich (M8159).
Immunogen
Name
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Phosphopeptide corresponding to phosphorylated threonine and tyrosine residues within the ERK-activation loop.
Sequence [+]
Reported Usage
immunohistochemistry
western blot
Publications
???displayAntibody.papersFirst??? A Raf/MEK/ERK signaling pathway is required for development of the sea urchin embryo micromere lineage through phosphorylation of the transcription factor Ets., Development 2004  
???displayAntibody.papersRecent??? Thyroid Hormones Accelerate Initiation of Skeletogenesis via MAPK (ERK1/2) in Larval Sea Urchins (Strongylocentrotus purpuratus)., Front Endocrinol (Lausanne) 2018                            
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