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Echinobase

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ECB-ANTIBODY-26395138

Antibody Name: phospho-LOC592760 Ab1

Common Name: phosphorylated myosin regulatory light chain 12B

RRID:
Synonyms: phospho-myosin II RLC, P-MyoRLC, Ser-19–phosphorylated myosin II regulatory light chain

Antigens
Gene: LOC592760

Clone Type: Monoclonal
Source: Cell Signaling Technology

Antibody
Clone Number
Purification
Isotype IgG1
Host Organism mouse
Echinoderm Reactivity S. purpuratus,
Non-Echinoderm Reactivity human, Lytechinus pictus, mouse, pig, rat
Description: Detects head domains of bipolar filaments in contractile structures in sea urchin embryos. Supplied by Cell Signaling Technology (#3675). Also tested on Strongylocentrotus droebachiensis.
Immunogen
Name Ser19
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Synthetic phosphopeptide that corresponds to amino acids surrounding the phosphorylated serine residue (Ser19) in smooth muscle.
Sequence
Reported Usage
immunohistochemistry
immunofluorescence
Publications
???displayAntibody.papersFirst??? Building the cytokinetic contractile ring in an early embryo: Initiation as clusters of myosin II, anillin and septin, and visualization of a septin filament network., PLoS One 2021     
???displayAntibody.papersRecent??? The nanoscale organization of the Wnt signaling integrator Dishevelled in the vegetal cortex domain of an egg and early embryo., PLoS One 2021     
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