ECB-ART-51186
Fly (Austin)
2022 Dec 01;161:347-359. doi: 10.1080/19336934.2022.2139981.
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Notch Signalling Under Maternal-to-Zygotic Transition.
Yamakawa T
,
Yuslimatin Mujizah E
,
Matsuno K
.
Abstract
The development of all animal embryos is initially directed by the gene products supplied by their mothers. With the progression of embryogenesis, the embryo's genome is activated to command subsequent developments. This transition, which has been studied in many model animals, is referred to as the Maternal-to-Zygotic Transition (MZT). In many organisms, including flies, nematodes, and sea urchins, genes involved in Notch signaling are extensively influenced by the MZT. This signaling pathway is highly conserved across metazoans; moreover, it regulates various developmental processes. Notch signaling defects are commonly associated with various human diseases. The maternal contribution of its factors was first discovered in flies. Subsequently, several genes were identified from mutant embryos with a phenotype similar to Notch mutants only upon the removal of the maternal contributions. Studies on these maternal genes have revealed various novel steps in the cascade of Notch signal transduction. Among these genes, pecanex and almondex have been functionally characterized in recent studies. Therefore, in this review, we will focus on the roles of these two maternal genes in Notch signaling and discuss future research directions on its maternal function.
PubMed ID: 36346359
Article link: Fly (Austin)
References [+] :
Austin,
glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans.
1987, Pubmed
Austin, glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. 1987, Pubmed
Bashirullah, Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastula transition in Drosophila melanogaster. 1999, Pubmed
Bushati, Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila. 2008, Pubmed
Cao, Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. 2020, Pubmed
Das, Maternal almondex, a neurogenic gene, is required for proper subcellular Notch distribution in early Drosophila embryogenesis. 2020, Pubmed
De Renzis, Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo. 2007, Pubmed
Foe, Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis. 1983, Pubmed
Fuss, Cell movements controlled by the Notch signalling cascade during foregut development in Drosophila. 2004, Pubmed
Gilbert, A mammalian homologue of a transcript from the Drosophila pecanex locus. 1992, Pubmed
Gildor, Comparative Study of Regulatory Circuits in Two Sea Urchin Species Reveals Tight Control of Timing and High Conservation of Expression Dynamics. 2015, Pubmed , Echinobase
Hamatani, Dynamics of global gene expression changes during mouse preimplantation development. 2004, Pubmed
Harrison, Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes. 2010, Pubmed
Hartenstein, Early neurogenesis in wild-typeDrosophila melanogaster. 1984, Pubmed
Hu, Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex. 2003, Pubmed
Jakobsdottir, Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. 2016, Pubmed
Jiménez, Maternal effects of zygotic mutants affecting early neurogenesis inDrosophila. 1982, Pubmed
Kajkowski, beta -Amyloid peptide-induced apoptosis regulated by a novel protein containing a g protein activation module. 2001, Pubmed
Kaufman, Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. 1999, Pubmed
Kelly, Maternally controlled (beta)-catenin-mediated signaling is required for organizer formation in the zebrafish. 2000, Pubmed
Kidd, Furin cleavage is not a requirement for Drosophila Notch function. 2002, Pubmed
Kopan, A common enzyme connects notch signaling and Alzheimer's disease. 2000, Pubmed
LaBonne, Molecular genetics of pecanex, a maternal-effect neurogenic locus of Drosophila melanogaster that potentially encodes a large transmembrane protein. 1989, Pubmed
Lake, In vivo analysis of the Notch receptor S1 cleavage. 2009, Pubmed
Lecourtois, The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling. 1995, Pubmed
Lee, XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. 2003, Pubmed
Lehmann, On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster. 1983, Pubmed
Lehmann, Mutations of early neurogenesis inDrosophila. 1981, Pubmed
Li, Direct full-length RNA sequencing reveals unexpected transcriptome complexity during Caenorhabditis elegans development. 2020, Pubmed
Li, Maternal control of early mouse development. 2010, Pubmed
Liang, The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila. 2008, Pubmed
Logeat, The Notch1 receptor is cleaved constitutively by a furin-like convertase. 1998, Pubmed
Lott, Noncanonical compensation of zygotic X transcription in early Drosophila melanogaster development revealed through single-embryo RNA-seq. 2011, Pubmed
Lécuyer, Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. 2007, Pubmed
López-Schier, Drosophila nicastrin is essential for the intramembranous cleavage of notch. 2002, Pubmed
Martín-Bermudo, Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification. 1995, Pubmed
Meloty-Kapella, Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin. 2012, Pubmed
Menchero, Transitions in cell potency during early mouse development are driven by Notch. 2019, Pubmed
Menne, The formation of commissures in the Drosophila CNS depends on the midline cells and on the Notch gene. 1994, Pubmed
Michellod, Differential requirements for the neurogenic gene almondex during Drosophila melanogaster development. 2003, Pubmed
Michellod, Implication of the Drosophila beta-amyloid peptide binding-like protein AMX in Notch signaling during early neurogenesis. 2008, Pubmed
Morisato, Signaling pathways that establish the dorsal-ventral pattern of the Drosophila embryo. 1995, Pubmed
Mumm, Notch signaling: from the outside in. 2000, Pubmed
Nien, Temporal coordination of gene networks by Zelda in the early Drosophila embryo. 2011, Pubmed
Perrimon, Developmental genetics of the 2E-F region of the Drosophila X chromosome: a region rich in "developmentally important" genes. 1984, Pubmed
Peterson, A Fringe-modified Notch signal affects specification of mesoderm and endoderm in the sea urchin embryo. 2005, Pubmed , Echinobase
Priess, The glp-1 locus and cellular interactions in early C. elegans embryos. 1987, Pubmed
Roux, Physical and transcription map in the region 14q24.3: identification of six novel transcripts. 1997, Pubmed
Salazar, TM2D genes regulate Notch signaling and neuronal function in Drosophila. 2021, Pubmed
Sasamura, neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions. 2003, Pubmed
Sasamura, The O-fucosyltransferase O-fut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila. 2007, Pubmed
Schulz, Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo. 2015, Pubmed
Seydoux, Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans. 1994, Pubmed
Shannon, Characterization of the female-sterile mutant almondex of Drosophila melanogaster. 1972, Pubmed
Shaye, OrthoList: a compendium of C. elegans genes with human orthologs. 2011, Pubmed
Shi, Canonical Notch signaling is dispensable for early cell fate specifications in mammals. 2005, Pubmed , Echinobase
Siddiqui, Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells. 2012, Pubmed
Simpson, Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila. 1990, Pubmed
Stephenson, Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region. 2012, Pubmed
Struhl, Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. 1993, Pubmed
Sturtevant, INHERITANCE OF DIRECTION OF COILLING IN LIMNAEA. 1923, Pubmed
Sun, Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation. 2015, Pubmed
Söllner, SNAP receptors implicated in vesicle targeting and fusion. 1993, Pubmed
Tadros, SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. 2007, Pubmed
Tadros, The maternal-to-zygotic transition: a play in two acts. 2009, Pubmed , Echinobase
Tao, Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos. 2005, Pubmed
Thomsen, Genome-wide analysis of mRNA decay patterns during early Drosophila development. 2010, Pubmed
Walton, Genomics and expression profiles of the Hedgehog and Notch signaling pathways in sea urchin development. 2006, Pubmed , Echinobase
Wang, Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila. 2005, Pubmed
Weeks, A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta. 1987, Pubmed
Wharton, Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. 1985, Pubmed
Wilson, A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast. 1989, Pubmed
Yamakawa, Deficient Notch signaling associated with neurogenic pecanex is compensated for by the unfolded protein response in Drosophila. 2012, Pubmed
Yamakawa, Insight into Notch Signaling Steps That Involve pecanex from Dominant-Modifier Screens in Drosophila. 2018, Pubmed
Ye, Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. 1999, Pubmed
Yochem, The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch. 1988, Pubmed
Yochem, glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins. 1989, Pubmed
Yoshida, A time-dependent phase shift in the mammalian unfolded protein response. 2003, Pubmed
Zheng, Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesis. 2009, Pubmed
ten Bosch, The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription. 2006, Pubmed