ECB-ART-51003Toxics 2022 Jun 24;107:. doi: 10.3390/toxics10070348.
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Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar Scaphechinus mirabilis Sperm.
Products containing nanomaterials are becoming more and more common in everyday life. Zinc oxide nanoparticles (ZnO NPs), meanwhile, are among the most widely used NPs. However, their genotoxic effect on the germ products of marine organisms is poorly understood. Therefore, the effects of ZnO NPs and zinc ions (20, 50, 100, 200 µg/L) on the sperm of sand dollar Scaphechinus mirabilis were compared. Comet assay showed that both tested pollutants caused an increase in DNA damage to 6.57 ± 2.41 and 7.42 ± 0.88% DNA in the comet tail, for zinc ions and ZnO NPs, respectively. Additionally, a different pattern was shown by the increase in DNA damage, with increasing concentration of pollutants, in different experimental groups.
PubMed ID: 35878253
PMC ID: PMC9318529
Article link: Toxics
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|Figure 1. Assessment of S.mirabilis sperm DNA damage from control and experimental groups. (A) Zn2+ exposure. (B) ZnO NPs exposure. (Mean ± standard deviation, N = 8, n = 400.) * Difference from the control is significant (p < 0.05).|