Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Variations in the phosphate content and thiołdisulphide ratio of histones during the cell cycle. Studies with regenerating rat liver and sea urchins.
Ord MG
,
Stocken LA
.
Abstract
1. In regenerating rat liver the phosphate content of the lysine-rich histone F1, but not that of the more arginine-rich histone F3-1, increases during the period of DNA synthesis. 2. The phosphorylation of histone F1 in this ;S period'' is decreased by gamma-irradiation, but, like phosphate uptake into DNA, is affected to an even greater extent if the irradiation is given in the presynthetic period. 3. Histones from three species of sea-urchin eggs show similarities to the F2 and F3 groups of histones from mammalian thymus gland. 4. The proportion of thiol to total thiol plus disulphide in acid extracts from sea-urchin eggs varies from less than 20% in mature unfertilized eggs to 59% just before cleavage. 5. The phosphorylated forms of histones F1 and F3 are less effective in decreasing DNA synthesis by DNA polymerase than the non-phosphorylated forms. 6. Oxidation of thiol groups on histone F3-1 does not affect its capacity to decrease DNA synthesis in vitro.
Bäckström,
Basic proteins in the sea urchin embryo (Paracentrotus lividus).
1965, Pubmed,
Echinobase
Bäckström,
Basic proteins in the sea urchin embryo (Paracentrotus lividus).
1965,
Pubmed
,
Echinobase
BARTLETT,
Phosphorus assay in column chromatography.
1959,
Pubmed
Berenblum,
An improved method for the colorimetric determination of phosphate.
1938,
Pubmed
BOLLUM,
Calf thymus polymerase.
1960,
Pubmed
Comb,
Synthesis of basic proteins and cellular RNA species during sea urchin development.
1966,
Pubmed
,
Echinobase
DELUCA,
Incorporation of radioactive phosphate into the nucleic acids of brain slices.
1953,
Pubmed
ELLMAN,
Tissue sulfhydryl groups.
1959,
Pubmed
Frenster,
Nuclear polyanions as de-repressors of synthesis of ribonucleic acid.
1965,
Pubmed
Gurdon,
On the origin and persistence of a cytoplasmic state inducing nuclear DNA synthesis in frogs' eggs.
1967,
Pubmed
Gurley,
Inhibition of DNA polymerase by histones.
1964,
Pubmed
Ingles,
Phosphorylation of protamine during spermatogenesis in trout testis.
1967,
Pubmed
JAFFE,
Diurnal mitotic periodicity in regenerating rat liver.
1954,
Pubmed
Johns,
Studies on histones. 7. Preparative methods for histone fractions from calf thymus.
1964,
Pubmed
LOWRY,
Protein measurement with the Folin phenol reagent.
1951,
Pubmed
Marsh,
Thiol proteins in nuclei from rat liver and thymus.
1964,
Pubmed
Mauritzen,
The fractionation of arginine-rich histones from fetal calf thymus by exclusion chromatography.
1967,
Pubmed
Ord,
Metabolic properties of histones from rat liver and thymus gland.
1966,
Pubmed
Ord,
Phosphate and thiol groups in histone f3 from rat liver and thymus nuclei.
1967,
Pubmed
ORD,
METABOLIC AND CHEMICAL PROPERTIES OF BASIC PROTEINS ISOLATED FROM NUCLEI OF RAT LIVER AND THYMUS GLAND.
1965,
Pubmed
Potter,
Enzyme levels in rats adapted to 36-hour fasting.
1966,
Pubmed
Sakai,
A ribonucleoprotein which catalyzes thiol-disulfide exchange in the sea urchin egg.
1967,
Pubmed
,
Echinobase
