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Echinobase
ECB-ART-32118
Biosci Rep 1988 Oct 01;85:415-9. doi: 10.1007/bf01121638.
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Proto-oncogene homologous sequences in the sea urchin genome.

Mifflin D , Robinson JJ .


Abstract
Using probes specific for several oncogenes/proto-oncogenes we have performed gel blot hybridization analyses of genomic DNA isolated from the sea urchin Strongylocentrotus droebachiensis. Probes prepared from v-erbB, v-myc, c-myb and v-fps were found to hybridize with discrete fragments of HindIII digested genomic DNA. In contrast, probes prepared from v-abl, v-fos, v-sis, v-src, and v-mos either hybridized with multiple fragments, indicating non-specific binding, or failed to hybridize at all above background levels. These results clearly demonstrate the presence of proto-oncogene homologous sequences in the sea urchin genome.

PubMed ID: 2852975
Article link: Biosci Rep


Genes referenced: abl2 LOC100887844 LOC100889124 LOC373385 LOC574936 LOC579838 mos mybb