Environ Pollut 2026 Jun 21;:128609. doi: 10.1016/j.envpol.2026.128609.

Interactive Effects of Triclosan, Microplastic Vectors, and Ocean Warming-Acidification on Sea Urchin Embryo Development.

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Understanding how emerging contaminants interact with climate-driven stressors is essential for accurate ecological risk assessment in coastal ecosystems. This study evaluates the individual and combined effects of triclosan (TC), polyethylene microplastics (MP), ocean warming (OW), and ocean acidification (OA) on the early development of Paracentrotus lividus embryos. A tiered experimental design was implemented to: (i) characterize TC dose-response curves alone and in combination with increasing concentrations of MP (300-3000 particles mL-1), and (ii) assess how OW (24 °C) and OA (pH 7.6) modulate contaminant toxicity. TC showed concentration-dependent growth inhibition, while MP exhibited a biphasic interaction with TC: at moderate concentrations, MP increased EC10 values and steepened dose-response slopes, consistent with contaminant sorption reducing freely dissolved TC. At 3000 particles mL-1, this trend reversed, lowering EC50 values and enhancing toxicity. Morphometric analyses revealed that co-exposure to TC alone and with MP loads impaired arm elongation, increased body-width ratios, and reduced stomach volume, indicating compromised feeding and skeletal development. Climate stressors significantly altered toxicological outcomes. OA strongly amplified the combined toxicity of TC + MP, reducing larval growth to near-zero levels, whereas OW alone did not exacerbate toxicity and partially mitigated OA-driven effects in MP-TC treated groups. Degree-day normalization demonstrated that warming accelerates development but reduces growth efficiency across treatments. Overall, these results reveal threshold-dependent MP-TC interactions and highlight acidification as a critical amplifier of contaminant effects. Incorporating realistic MP-pollutant interactions and climate variables is crucial for improving hazard assessments under future ocean scenarios.

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