Spectrochim Acta A Mol Biomol Spectrosc 2024 Jan 15;305:123464. doi: 10.1016/j.saa.2023.123464.

Preparation of 3D nano silver trees/sea urchin-like gold and SERS detection of uric acid.

???displayArticle.abstract???
In this paper, 3D nano-silver trees/sea urchin-like gold Surface Enhanced Raman Spectroscopy (SERS) substrates were prepared by chemical reduction method, characterized by SEM, EDS, UV-Vis and XRD et.al, and the preparation process was optimized using Rhodamine B (RB) as the Raman signal molecule. The SERS characteristics of Uric Acid on this substrate were investigated and the results showed that the SERS substrate had a Raman enhancement factor of 1.9 × 107 for RB, and also had a significant Raman enhancement effect on Uric Acid. The SERS intensity (ISERS) at 1400 cm-1 showed a good linear relationship with the logarithm value of uric acid concentration (log C) between the range of 5 × 10-4 M to 1 × 10-7 M. The linear fitting equation was ISERS = 890 (log C) + 8066 (R2 = 0.983), and the LOD = 2.8 × 10-8 M. The spiked test was performed in human serum with recoveries ranging from 82.86% to 125.13% and RSD (n = 3) < 3.5%.

???displayArticle.pubmedLink??? 37837927
???displayArticle.link??? Spectrochim Acta A Mol Biomol Spectrosc