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Echinobase
ECB-ART-52503
Dev Growth Differ 1989 Feb 01;311:17-21. doi: 10.1111/j.1440-169X.1989.00017.x.
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Deprenyl, an Inhibitor of Monoamine Oxidase B, Delays the First Two Mitotic Cycles of Sea Urchin eggs: (deprenyl/mitotic cylcle/sea urchin).

Nicotra A , Serafino A , Arizzi M .


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Sea urchin eggs are known to display a significant level of monoamine oxidase B activity. Deprenyl, a highly selective inhibitor of monoamine oxidase B, was found to prolong the length of the first two mitotic cycles of the sea urchin egg. The prophase seems to be specifically prolonged by the drug, while the length of the other phases of the cycle is unaffected. These results suggest that the monoamine oxidase B may be a component of the monoaminergic system acting during the divisions of the sea urchin eggs.

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