Dev Growth Differ 1972 May 01;141:63-74. doi: 10.1111/j.1440-169X.1972.00063.x.

OCCURRENCE OF MUCOPOLYSACCHARIDES IN THE EARLY DEVELOPMENT OF THE SEA URCHIN EMBRYO AND ITS ROLE IN GASTRULATION.

???displayArticle.abstract???
The occurrence of acid mucopolysaccharides in the early development of the sea urchin embryo was studied by histochemical stainings as well as by autoradiographic methods. By histochemical methods acid niucopolysacchdride was demonstrated at the vegetal region in the early stage of gastrulation as a globular structure. Experiments with 35 S-labeled sulfate which was incorporated into acid mucopolysaccharides confirmed the result obtained by histochemical observation. It was revealed that sulfate polysaccharide in the vegetal region moved toward the blastocoel in parallel with the shedding of the primary mesenchyme cells. When the incorporation of sulfate into the acid mucopolysaccharides was inhibited by selenate, the primitive gut development was remarkably repressed. The substance seems to be indispensable for smooth cell movements essential for the gastrulation of sea urchin embryo.

???displayArticle.pubmedLink??? 37281885
???displayArticle.link??? Dev Growth Differ