Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Antibiotics (Basel)
2022 Dec 17;1112:. doi: 10.3390/antibiotics11121835.
Show Gene links
Show Anatomy links
Genomic Analysis of Klebsiella pneumoniae ST258 Strain Coproducing KPC-2 and CTX-M-14 Isolated from Poultry in the Brazilian Amazon Region.
Valiatti TB
,
Cayô R
,
Santos FF
,
Bessa-Neto FO
,
Brandão Silva RG
,
Veiga R
,
de Nazaré Miranda Bahia M
,
Guerra LMGD
,
Pignatari ACC
,
de Oliveira Souza C
,
Brasiliense DM
,
Gales AC
,
Guarani Network
.
???displayArticle.abstract???
This study aimed to characterize a Klebsiella pneumoniae strain (KP411) recovered from the stool samples of poultry (Gallus gallus) in the Brazilian Amazon Region. The whole-genome sequencing of KP411 revealed the presence of an important arsenal of antimicrobial resistance genes to β-lactams (blaCTX-M-14, blaTEM-1B, blaKPC-2, blaSVH-11), aminoglycosides [aph(3″)- Ib, aph(6)-Id, aph(3')-Ia], sulfonamides (sul1, sul2), quinolones (oqxAB), fosfomycin (fosAKP), and macrolides [mph(A)]. Furthermore, our analyses revealed that the KP411 strain belongs to the ST258 clonal lineage, which is one of the main epidemic clones responsible for the dissemination of KPC-2 worldwide. Our data suggest that food-producing animals may act as reservoirs of multidrug-resistant K. pneumoniae belonging to the ST258 clone, and, consequently, contribute to their dissemination to humans and the environment.
Aires,
Population Structure of KPC-2-Producing Klebsiella pneumoniae Isolated from Surveillance Rectal Swabs in Brazil.
2020, Pubmed
Aires,
Population Structure of KPC-2-Producing Klebsiella pneumoniae Isolated from Surveillance Rectal Swabs in Brazil.
2020,
Pubmed
Andrade,
Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil.
2011,
Pubmed
Andrey,
An Emerging Clone, Klebsiellapneumoniae Carbapenemase 2-Producing K. pneumoniae Sequence Type 16, Associated With High Mortality Rates in a CC258-Endemic Setting.
2020,
Pubmed
Bankevich,
SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing.
2012,
Pubmed
Bolger,
Trimmomatic: a flexible trimmer for Illumina sequence data.
2014,
Pubmed
Chuang,
Genetic determinants of capsular serotype K1 of Klebsiella pneumoniae causing primary pyogenic liver abscess.
2006,
Pubmed
Fang,
A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications.
2004,
Pubmed
Fontana,
Small IncQ1 Plasmid Encoding KPC-2 Expands to Invasive Nontyphoidal Salmonella.
2021,
Pubmed
Ho,
Molecular Characterization of an Atypical IncX3 Plasmid pKPC-NY79 Carrying bla KPC-2 in a Klebsiella pneumoniae.
2013,
Pubmed
Hsu,
The role of Klebsiella pneumoniae rmpA in capsular polysaccharide synthesis and virulence revisited.
2011,
Pubmed
Jean,
Global Threat of Carbapenem-Resistant Gram-Negative Bacteria.
2022,
Pubmed
Johnson,
Type 3 fimbriae and biofilm formation are regulated by the transcriptional regulators MrkHI in Klebsiella pneumoniae.
2011,
Pubmed
Kanukollu,
Contribution of the traT gene to serum resistance among clinical isolates of enterobacteriaceae.
1985,
Pubmed
Kopotsa,
Plasmid evolution in carbapenemase-producing Enterobacteriaceae: a review.
2019,
Pubmed
Lee,
Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods.
2016,
Pubmed
Lee,
Hypermucoviscosity associated with Klebsiella pneumoniae-mediated invasive syndrome: a prospective cross-sectional study in Taiwan.
2010,
Pubmed
Letunic,
Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation.
2007,
Pubmed
Li,
The pathogenicity of rmpA or aerobactin-positive Klebsiella pneumoniae in infected mice.
2019,
Pubmed
Liakopoulos,
Genomic and functional characterisation of IncX3 plasmids encoding blaSHV-12 in Escherichia coli from human and animal origin.
2018,
Pubmed
Moll,
Plasmid-determined resistance to serum bactericidal activity: a major outer membrane protein, the traT gene product, is responsible for plasmid-specified serum resistance in Escherichia coli.
1980,
Pubmed
Nordmann,
Carbapenem resistance in Enterobacteriaceae: here is the storm!
2012,
Pubmed
Nordmann,
Global spread of Carbapenemase-producing Enterobacteriaceae.
2011,
Pubmed
Nordmann,
Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria.
2019,
Pubmed
Partridge,
Emergence of blaKPC carbapenemase genes in Australia.
2015,
Pubmed
Pitout,
Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance.
2015,
Pubmed
Remschmidt,
Surveillance of Antibiotic Use and Resistance in Intensive Care Units (SARI).
2017,
Pubmed
Seemann,
Prokka: rapid prokaryotic genome annotation.
2014,
Pubmed
Snyder,
PATRIC: the VBI PathoSystems Resource Integration Center.
2007,
Pubmed
Szijártó,
Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against Klebsiella pneumoniae ST258.
2017,
Pubmed
Van Boeckel,
Global trends in antimicrobial use in food animals.
2015,
Pubmed
Xiong,
Antimicrobial use and antimicrobial resistance in food animals.
2018,
Pubmed
Yang,
High rate of multiresistant Klebsiella pneumoniae from human and animal origin.
2019,
Pubmed
de Carvalho,
Exploring the Bacteriome and Resistome of Humans and Food-Producing Animals in Brazil.
2022,
Pubmed
,
Echinobase
