Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-51822
Front Nutr 2022 Jan 01;9:1011732. doi: 10.3389/fnut.2022.1011732.
Show Gene links Show Anatomy links

Butyrate: Connecting the gut-lung axis to the management of pulmonary disorders.

Corrêa RO , Castro PR , Moser R , Ferreira CM , Quesniaux VFJ , Vinolo MAR , Ryffel B .


???displayArticle.abstract???
Short-chain fatty acids (SCFAs) are metabolites released by bacterial components of the microbiota. These molecules have a wide range of effects in the microbiota itself, but also in host cells in which they are known for contributing to the regulation of cell metabolism, barrier function, and immunological responses. Recent studies indicate that these molecules are important players in the gut-lung axis and highlight the possibility of using strategies that alter their intestinal production to prevent or treat distinct lung inflammatory diseases. Here, we review the effects of the SCFA butyrate and its derivatives in vitro and in vivo on murine models of respiratory disorders, besides discussing the potential therapeutic use of butyrate and the other SCFAs in lung diseases.

???displayArticle.pubmedLink??? 36337621
???displayArticle.link??? Front Nutr



References [+] :
Albouery, Soluble Fiber Inulin Consumption Limits Alterations of the Gut Microbiota and Hepatic Fatty Acid Metabolism Caused by High-Fat Diet. 2021, Pubmed