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Med Hypothesis Discov Innov Ophthalmol
2021 Jan 01;102:67-73. doi: 10.51329/mehdiophthal1423.
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Comparison of optical coherence tomography angiography features in type 1 versus type 2 choroidal neovascular membranes secondary to age-related macular degeneration.
Goker YS
,
Demir G
.
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BACKGROUND: Optical coherence tomography angiography (OCTA) is an advanced imaging modality that provides high resolution images at the level of different retinal layers. This study aime to evaluate choroidal neovascular membranes (CNVMs) secondary to age-related macular degeneration (AMD) quantitatively and qualitatively, according to their classification, morphological features, and flow areas, using OCTA.
METHODS: In this descriptive, comparative, cross-sectional study, CNVMs were divided into 2 groups according to their classification as type 1 or type 2 neovascularization. Mied CNVMs were excluded from the study. The size (mm2) and the flow area (mm2) of the CNVMs were calculated via OCTA and the presence of the perivascular halo and loop anastomoses were analyzed. The morphological appearance of the CNVMs were classified as: medusa, sea-fan, lacy-wheel, glomerular, dead tree, and mature vascular networks.
RESULTS: Of the 85 eyes assessed for eligibility, 45 eyes of 34 individuals with CNVM were enrolled in this retrospective study. Twenty-eight eyes had type 1 and 17 eyes had type 2 CNVMs. The mean size and flow area were greater in type 1 than in type 2 CNVMs (mean [standard deviation], 6.69 [4.54] and 3.61 [3.56] mm2 versus 3.04 [1.98] and 1.77 [1.62] mm2; P = 0.044 and 0.046, respectively). Among the 22 eyes with type 1 CNVMs and the 9 eyes with type 2 CNVMs, 31 eyes had exudative membranes. Among the eyes with exudative CNVMs, 22 eyes had a perivascular halo and 22 eyes had loop anastomoses; this was significantly more than in the non-exudative eyes (P = 0.042 and 0.041, respectively). The lacy-wheel (38.7%) and dead tree (71.4%) patterns were the most frequent morphological appearance of the CNVMs in the exudative and non-exudative membranes, respectively.
CONCLUSIONS: OCTA provides objective documantation about CNVMs. A perivascular dark halo around CNVMs could be a criterion to define exudative membranes activity.
Cheung,
IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.
2019, Pubmed
Cheung,
IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.
2019,
Pubmed
Cohen,
Types of choroidal neovascularisation in newly diagnosed exudative age-related macular degeneration.
2007,
Pubmed
Coscas,
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY VERSUS TRADITIONAL MULTIMODAL IMAGING IN ASSESSING THE ACTIVITY OF EXUDATIVE AGE-RELATED MACULAR DEGENERATION: A New Diagnostic Challenge.
2015,
Pubmed
El Ameen,
TYPE 2 NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.
2015,
Pubmed
Farecki,
Characteristics of type 1 and 2 CNV in exudative AMD in OCT-Angiography.
2017,
Pubmed
Freund,
Do we need a new classification for choroidal neovascularization in age-related macular degeneration?
2010,
Pubmed
Jung,
The incidence of neovascular subtypes in newly diagnosed neovascular age-related macular degeneration.
2014,
Pubmed
Karacorlu,
Membrane patterns in eyes with choroidal neovascularization on optical coherence tomography angiography.
2019,
Pubmed
,
Echinobase
Kuehlewein,
Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration.
2015,
Pubmed
Lupidi,
Optical coherence tomography angiography in age-related macular degeneration: The game changer.
2018,
Pubmed
Menteş,
Optical Coherence Tomography Characteristics of Quiescent Type 1 Neovascularization in Eyes with Nonexudative Age-related Macular Degeneration.
2019,
Pubmed
Miere,
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF SUBRETINAL FIBROSIS IN AGE-RELATED MACULAR DEGENERATION.
2015,
Pubmed
Muakkassa,
CHARACTERIZING THE EFFECT OF ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ON TREATMENT-NAIVE CHOROIDAL NEOVASCULARIZATION USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.
2015,
Pubmed
Resnikoff,
Global data on visual impairment in the year 2002.
2004,
Pubmed
Soomro,
The use of optical coherence tomography angiography for detecting choroidal neovascularization, compared to standard multimodal imaging.
2018,
Pubmed
Spaide,
Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography.
2015,
Pubmed
Witmer,
Vascular endothelial growth factors and angiogenesis in eye disease.
2003,
Pubmed
Xu,
Long-term Progression of Type 1 Neovascularization in Age-related Macular Degeneration Using Optical Coherence Tomography Angiography.
2018,
Pubmed
Yannuzzi,
Retinal angiomatous proliferation in age-related macular degeneration.
2001,
Pubmed
Zhao,
The Comparison of Morphologic Characteristics of Type 1 and Type 2 Choroidal Neovascularization in Eyes with Neovascular Age-Related Macular Degeneration using Optical Coherence Tomography Angiography.
2019,
Pubmed
