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ECB-ART-51562
Fish Shellfish Immunol 2023 Apr 01;135:108662. doi: 10.1016/j.fsi.2023.108662.
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Dietary fulvic acid supplementation improves the growth performance and immune response of sea cucumber (Apostichopus japonicas).

Dou H , Wu S .


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The present study aims to explore the effects of dietary fulvic acid (FA) supplementation on the growth performance, digestive enzyme activity and immune response of sea cucumber (Apostichopus japonicas). FA was used to replace 0 (control), 0.1, 0.5 and 1 g cellulose in the basic diet of sea cucumber to formulate four experimental feeds with equivalent nitrogen and energy denoted as F0, F0.1, F0.3 and F1, respectively. No significant differences were observed in the survival rate among all groups (P > 0.05). Results show that the body weight gain rate, specific growth rate, intestinal trypsin, amylase and lipase activities, serum superoxide dismutase, catalase, lysozyme, alkaline and acid phosphatase activities and disease resistance ability against the pathogen, Vibrio splendidus of the sea cucumbers fed with FA-containing diets were significantly higher than those of the control group (P < 0.05). The optimum dose of dietary FA supplementation required for the maximum growth of sea cucumber was 0.54 g/kg. Therefore, dietary FA supplementation to the feed of sea cucumber can significantly improve its growth performance immune response.

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???displayArticle.link??? Fish Shellfish Immunol