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ECB-ART-51378
J Asian Nat Prod Res 2023 Jun 06;:1-7. doi: 10.1080/10286020.2023.2219616.
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Asterosaponins from the starfish Protoreaster nodosus.

Vien LT , Hanh TTH , Quang TH , Thanh NV , Cuong NX , Nam NH , Do Cong T , Kiem PV .


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Five asterosaponins (1-5), including one new compound named protonodososide (1), were isolated from the methanol extract of the starfish Protoreaster nodosus, after subjecting to various chromatographic separations. The structural elucidation was confirmed by careful analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. The cytotoxicity of isolated compounds was evaluated on five human cancer cell lines including HepG2, KB, MCF7, LNCaP, and SK-Mel2.

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