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ECB-ART-51344
RSC Med Chem 2023 Jun 22;146:1049-1059. doi: 10.1039/d3md00035d.
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Polysaccharides from marine biological resources and their anticancer activity on breast cancer.

Yang S , Li D , Liu W , Chen X .


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In recent decades, natural products from marine organisms have been widely studied for the treatment of various breast cancers. Among them, polysaccharides have been favored by researchers because of their good effects and safety. In this review, polysaccharides from marine algae including macroalgae and microalgae, chitosan, microorganisms such as marine bacteria and fungi, and starfish are addressed. Their anticancer activities on different breast cancers and action mechanisms are discussed in detail. In general, polysaccharides from marine organisms are potential sources of low side-effect and high efficiency anticancer drugs for development. However, further research on animals and clinical research are needed.

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References [+] :
Abd-Ellatef, Ulva lactuca polysaccharides prevent Wistar rat breast carcinogenesis through the augmentation of apoptosis, enhancement of antioxidant defense system, and suppression of inflammation. 2017, Pubmed