Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-50221
Amino Acids 1994 Feb 01;61:1-13. doi: 10.1007/BF00808118.
Show Gene links Show Anatomy links

Distribution and biological activity ofβ-thymosins.

Mihelić M , Voelter W .


???displayArticle.abstract???
β-Thymosins, a group of highly homologous peptides consisting of about 40 amino acid residues, were found to be distributed from mammals up to echinoderms. Althogh they have first been isolated from mammalian thymus tissue preparations, their occurrance is not organ-specific and they are present even in different types of cells. For thymosinβ 4 several biological activities have been reported, stating that this peptide acts as a thymus peptide hormone and is also involved in the neuroendocrine and immune system. However, it was recently demonstrated that thymosinβ 4 has actin-sequestering properties and therefore might play an important role in the regulation of the microfilament system. This fact gives a new outlook on the real biological function ofβ-thymosins.

???displayArticle.pubmedLink??? 24190738
???displayArticle.link??? Amino Acids



References [+] :
Abiko, Synthesis of a thymosin beta 4-like peptide, thymosin beta Met9, and its effect on low E-rosette-forming lymphocytes of lupus nephritis patients. 1990, Pubmed