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ECB-ART-48695
Rev Soc Bras Med Trop 2019 Dec 20;53:e20180498. doi: 10.1590/0037-8682-0498-2018.
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Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption.

Ribeiro ÁCDS , Crozatti MTL , Silva AAD , Macedo RS , Machado AMO , Silva ATA .


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INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.

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Genes referenced: impact

References [+] :
Baumgart, Prevalence of carbapenem resistant Pseudomonas aeruginosa and Acinetobacter baumannii in high complexity hospital. 2010, Pubmed