ECB-ART-47972
FEBS Lett
1992 May 18;3023:284-6. doi: 10.1016/0014-5793(92)80460-x.
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Selective inhibition of membrane fusion events in echinoderm gametes and embryos by halenaquinol sulfate.
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Halenaquinol sulfate, a hydroquinone sulfate obtained from the sponge Xestospongia sapra, prevented cell membrane fusion events of echinaderm gametes but did not affect early embryonic development of fertilized eggs up to the gastrula stage. However, halenaquinol sulfate inhibited secretion of hatching enzyme, resulting in the formation of gastrulae that were surrounded by the fertilization envelope. Therefore, the use of halenaquinol sulfate offers a unique opportunity to analyze the role of secretory events in complex populations of cells without affecting other cellular functions.
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Genes referenced: LOC115919910 mmp7