ECB-ART-47580
Biosci Biotechnol Biochem
2001 Nov 01;6511:2569-72. doi: 10.1271/bbb.65.2569.
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Synthesis of (R)-(+)-hippospongic acid A, a triterpene isolated from the marine sponge, Hippospongia sp.
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Hippospongic acid A (1) is a triterpene metabolite of the marine sponge, Hippospongia sp., with inhibitory activity against the gastrulation of starfish embryos. (R)-(+)-1 was synthesized by employing enzymatic kinetic resolution as the key step.
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