Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Environ Sci Pollut Res Int
2019 Jul 01;2620:20573-20580. doi: 10.1007/s11356-019-05279-8.
Show Gene links
Show Anatomy links
Assessment of individual and mixed toxicity of bromoform, tribromoacetic-acid and 2,4,6 tribromophenol, on the embryo-larval development of Paracentrotus lividus sea urchin.
Lebaron K
,
Mechiri L
,
Richard S
,
Austruy A
,
Boudenne JL
,
Coupé S
.
???displayArticle.abstract???
Water chlorination is the most widely used technique to avoid microbial contamination and biofouling. Adding chlorine to bromide-rich waters leads to the rapid oxidation of bromide ions and leads to the formation of brominated disinfection by-products (bromo-DBPs) that exert adverse effects on various biological models. Bromo-DBPs are regularly encountered within industrialized embayments, potentially impacting marine organisms. Of these, bromoform, tribromoacetic acid and tribromophenol are among the most prevalent. In the present study, we tested the potential toxicity and genotoxicity of these disinfection by-products, using sea urchin, Paracentrotus lividus, embryos. We highlighted that tribromophenol showed higher toxicity compared to bromoform and tribromoacetic acid. Furthermore, a synergistic effect was detected when tested in combination. Pluteus cells exposed for 1 h to mixtures of DBPs at several concentrations demonstrated significant DNA damage. Finally, when compared to a non-exposed population, sea urchins living in a bromo-DPB-polluted area produced more resistant progenies, as if they were locally adapted. This hypothesis remains to be tested in order to better understand the obvious impact of complex bromo-DBPs environments on marine wildlife.
Allonier,
Determination of dihaloacetonitriles and halophenols in chlorinated sea water.
1999, Pubmed
Allonier,
Determination of dihaloacetonitriles and halophenols in chlorinated sea water.
1999,
Pubmed
Bellas,
Integrative assessment of coastal pollution in a Ría coastal system (Galicia, NW Spain): correspondence between sediment chemistry and toxicity.
2008,
Pubmed
,
Echinobase
Boudjellaba,
Chlorination by-product concentration levels in seawater and fish of an industrialised bay (Gulf of Fos, France) exposed to multiple chlorinated effluents.
2016,
Pubmed
Collins,
The comet assay for DNA damage and repair: principles, applications, and limitations.
2004,
Pubmed
Delacroix,
Disinfection by-products and ecotoxicity of ballast water after oxidative treatment--results and experiences from seven years of full-scale testing of ballast water management systems.
2013,
Pubmed
Deng,
Chronic exposure to environmental levels of tribromophenol impairs zebrafish reproduction.
2010,
Pubmed
Dorey,
Development of the sea urchin Heliocidaris crassispina from Hong Kong is robust to ocean acidification and copper contamination.
2018,
Pubmed
,
Echinobase
Gharred,
Assessment of the individual and mixture toxicity of cadmium, copper and oxytetracycline, on the embryo-larval development of the sea urchin Paracentrotus lividus.
2016,
Pubmed
,
Echinobase
Gyori,
OpenComet: an automated tool for comet assay image analysis.
2014,
Pubmed
Halpern,
A global map of human impact on marine ecosystems.
2008,
Pubmed
Hanigan,
Zebrafish embryo toxicity of 15 chlorinated, brominated, and iodinated disinfection by-products.
2017,
Pubmed
Hose,
Potential uses of sea urchin embryos for identifying toxic chemicals: description of a bioassay incorporating cytologic, cytogenetic and embryologic endpoints.
1985,
Pubmed
,
Echinobase
Liu,
Comparative toxicity of new halophenolic DBPs in chlorinated saline wastewater effluents against a marine alga: halophenolic DBPs are generally more toxic than haloaliphatic ones.
2014,
Pubmed
Manasfi,
Assessing the genotoxicity of two commonly occurring byproducts of water disinfection: Chloral hydrate and bromal hydrate.
2017,
Pubmed
Manasfi,
Occurrence and speciation of chlorination byproducts in marine waters and sediments of a semi-enclosed bay exposed to industrial chlorinated effluents.
2019,
Pubmed
Messinetti,
Effects of polystyrene microplastics on early stages of two marine invertebrates with different feeding strategies.
2018,
Pubmed
,
Echinobase
Morroni,
Development of a new integrative toxicity index based on an improvement of the sea urchin embryo toxicity test.
2016,
Pubmed
,
Echinobase
Nahon,
Improved Comet assay for the assessment of UV genotoxicity in Mediterranean sea urchin eggs.
2008,
Pubmed
,
Echinobase
Neves,
Effects of the toxic benthic dinoflagellate Ostreopsis cf. ovata on fertilization and early development of the sea urchin Lytechinus variegatus.
2018,
Pubmed
,
Echinobase
Olive,
DNA double-strand breaks measured in individual cells subjected to gel electrophoresis.
1991,
Pubmed
Pereira,
Effects of the water-soluble fraction of diesel oil (WSD) on the fertilization and development of a sea urchin (Echinometra lucunter).
2018,
Pubmed
,
Echinobase
Richardson,
Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research.
2007,
Pubmed
Richardson,
What's in the pool? A comprehensive identification of disinfection by-products and assessment of mutagenicity of chlorinated and brominated swimming pool water.
2010,
Pubmed
Ríos,
Tribromophenol induces the differentiation of SH-SY5Y human neuroblastoma cells in vitro.
2003,
Pubmed
Taban,
Detection of DNA damage in mussels and sea urchins exposed to crude oil using comet assay.
2004,
Pubmed
,
Echinobase
Teixidó,
Developmental effects and genotoxicity of 10 water disinfection by-products in zebrafish.
2015,
Pubmed
Tice,
Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing.
2000,
Pubmed
Trifuoggi,
Comparative toxicity of seven rare earth elements in sea urchin early life stages.
2017,
Pubmed
,
Echinobase
Tu,
Sea urchin Forkhead gene family: phylogeny and embryonic expression.
2006,
Pubmed
,
Echinobase
Villanueva,
Disinfection byproducts and bladder cancer: a pooled analysis.
2004,
Pubmed
Villanueva,
Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in pools.
2007,
Pubmed
Westerhoff,
Reactivity of natural organic matter with aqueous chlorine and bromine.
2004,
Pubmed
Xiang,
Is Hydrogen Peroxide a Suitable Apoptosis Inducer for All Cell Types?
2016,
Pubmed
Yang,
Comparative developmental toxicity of new aromatic halogenated DBPs in a chlorinated saline sewage effluent to the marine polychaete Platynereis dumerilii.
2013,
Pubmed
Yildiz,
Determination of genotoxic effects of copper sulphate and cobalt chloride in Allium cepa root cells by chromosome aberration and comet assays.
2009,
Pubmed
Yoshioka,
Testing for the toxicity of chemicals with Tetrahymena pyriformis.
1985,
Pubmed
