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Echinobase
ECB-ART-46349
Dev Cell 2018 May 21;454:421-423. doi: 10.1016/j.devcel.2018.05.007.
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The Incredible Shrinking Spindle.

Brownlee C , Heald R .


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As cell size decreases during the reductive divisions of early development, intracellular structures must shrink to fit. In this issue of Developmental Cell, Lacroix et al. (2018) identify a conserved mechanism of spindle scaling in nematode and sea urchin embryos whereby spindle microtubule polymerization rates decrease as development proceeds.

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Genes referenced: LOC100887844 LOC115919910