ECB-ART-46220
Fitoterapia
2018 Jun 01;127:356-361. doi: 10.1016/j.fitote.2018.03.012.
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New isocoumarins, naphthoquinones, and a cleistanthane-type diterpene from Nectria pseudotrichia 120-1NP.
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Four new compounds, namely, nectriapyrones A (2) and B (3), nectriaquinone B (5), and zythiostromic acid C (8), were isolated from the brown rice culture of Nectria pseudotrichia 120-1NP together with four known compounds (1, 4, 6, and 7). To the best of our knowledge, this is the first report of 4 from a natural source. Their structures were determined on the basis of 1D/2D-NMR spectroscopy and HRESITOFMS data. In addition, the absolute configuration of secondary alcohols in 8 were determined using modified Mosher''s ester method. All isolated compounds were evaluated for their antimicrobials activity, phytotoxicity, and cytotoxicity.
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