Moira R et al. (2015), Epithelioid hemangioma of brachial artery: repo...

ECB-ART-45384

Open Med (Wars) 2015 Dec 17;101:502-507. doi: 10.1515/med-2015-0085.

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Epithelioid hemangioma of brachial artery: report of a case and review of the literature.

Moira R , Giuseppe F , Riccardo V , Nicola R , Daniele B , Pierfrancesco C , Antonio DC , Antonello A , Bruno A , Giovanni C , Guglielmo F .

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Epithelioid hemangioma (EH) is an uncommon benign vascular lesion, also known as angioblastic lymphoid (or angiolymphoid) hyperplasia with eosinophilia, characterized by an unclear etiopathogenesis. It usually affects young to middle-aged adults and develops in the head and neck region, as painless cutaneous or subcutaneous reddish papules or nodules. Large vessels involvement is extremely rare, and to date only two cases affecting the brachial artery have been cited in literature. In this report we present a further case of EH of the brachial artery and review the pertinent literature.

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Genes referenced: LOC115925415 LOC579152

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References [+] :

Abrahim, Epithelioid hemangioma of the internal carotid artery: a case report supporting the reactive pathogenesis hypothesis of this vascular tumor. 2014, Pubmed

	Figure 1. Ultrasound (US) of brachial artery showed a hypoechoic homogeneous well circumscribed solid lesion (L) arising from brachial artery (A); color Doppler showing peripheral and penetrating vascular network (B,C,D).
	Figure 2. Magnetic Resonance Imaging (MRI) of the left upper extremity showed a lesion (L) localized in the septum between the brachioradial and the rotund pronator muscle. Both SPIR (A) and STIR (B) images revealed a dishomogeneous hypointense enhancement relative to muscle tissues.
	Figure 3. Macroscopic examination. A well-defined encapsulated mass encasing a segment of vessel was resected (arrows) (A); on cross-section the mass was made of brownish hemorrhagic appearing tissue, and the arterial lumen was evident at the periphery of the nodule (arrow) (B).
	Figure 4. Histologic appearance. At low magnification the arterial lumen was compressed and dislocated by a thickening of the tunica media of the vessel wall, that is replaced by fibrotic tissue with conspicuous hemosiderin deposits and vessels proliferation (A). At high magnification a heavy chronic inflammatory infiltrate including numerous eosinophils was present (B) and small irregular vessels proliferation (C) with prominent endothelial cells were also evident (D).