ECB-ART-44931
J Nat Prod
2016 Oct 28;7910:2754-2757. doi: 10.1021/acs.jnatprod.6b00701.
Show Gene links
Show Anatomy links
Curacin E from the Brittle Star Ophiocoma scolopendrina.
???displayArticle.abstract???
Bioassay-guided fractionation of the extract of the brittle star Ophiocoma scolopendrina afforded curacin E (1), a congener of curacin A (2). Curacin A (2) is an antimitotic agent of cyanobacterial origin. The structure of curacin E was studied by interpretation of NMR data and the ECD spectrum. Curacin E has an ethylcarbonyl terminus in its side chain and inhibits the proliferation of P388 cells.
???displayArticle.pubmedLink??? 27684202
???displayArticle.link??? J Nat Prod
Genes referenced: ecd