ECB-ART-43815
Bull Environ Contam Toxicol
2015 Apr 01;944:419-24. doi: 10.1007/s00128-015-1482-z.
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Spermiotoxicity and embryotoxicity of permethrin in the sea urchin Paracentrotus lividus.
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The toxicity of permethrin on the fertilization and early development of sea urchin Paracentrotus lividus embryos were studied. Spermiotoxicity was evaluated on the basis of fertilization rate. Embryotoxicity was determined by comparing the frequency of normal development and malformations in embryos exposed to permethrin throughout their development. Permethrin inhibited fertilization success, and yielded IC25 and IC50 values of 0.58 (CL = 0.44-0.77) and 0.94 (CL = 0.92-0.95) µg/L, respectively. The embryotoxicity of permethrin was concentration dependent indicating a decreased percentage of normally developed plutei with increasing permethrin concentrations: IC25 = 0.195 µg/L (CL = 0.15-0.26) and IC50 = 0.346 µg/L (CF = 0.29-0.41). Associated with the decrease in normal pluteus frequency was an increase in larval malformations as skeleton deformities. The results suggest that permethrin is more highly toxic to embryos than to sperm, and that this insecticide may present a potential risk for the sea urchin in contaminated marine environments.
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Genes referenced: LOC100887844