Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Philos Trans R Soc Lond B Biol Sci
2014 Sep 05;3691650:. doi: 10.1098/rstb.2013.0455.
Show Gene links
Show Anatomy links
One to only two: a short history of the centrosome and its duplication.
Sluder G
.
???displayArticle.abstract???
This review discusses some of the history of the fundamental, but not fully solved problem of how the centrosome duplicates from one to only two as the cell prepares for mitosis. We start with some of the early descriptions of the centrosome and the remarkably prescient but then controversial inferences drawn concerning its function in the cell. For more than 100 years, one of the most difficult issues for the concept of the centrosome has been to integrate observations that centrosomes appear to be important for spindle assembly in animal cells yet are not evident in higher plant cells and some animal cells. This stirred debate over the existence of centrosomes and their importance. A parallel debate concerned the role of the centrioles in organizing centrosomes. The relatively recent elucidation of bipolar spindle assembly around chromatin allows a re-examination of the role of centrioles in controlling centrosome duplication in animal cells. The problem of how centrosomes precisely double in preparation for mitosis in animal cells has now moved to the mystery of how only one procentriole is assembled at each mother centriole.
Arquint,
Cell-cycle-regulated expression of STIL controls centriole number in human cells.
2012, Pubmed
Arquint,
Cell-cycle-regulated expression of STIL controls centriole number in human cells.
2012,
Pubmed
Basto,
Flies without centrioles.
2006,
Pubmed
Beisson,
Basal body/centriole assembly and continuity.
2003,
Pubmed
Bobinnec,
Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells.
1998,
Pubmed
Bornens,
The centrosome in cells and organisms.
2012,
Pubmed
Boveri,
Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris.
2008,
Pubmed
Brinkley,
The effects of colcemid inhibition and reversal on the fine structure of the mitotic apparatus of Chinese hamster cells in vitro.
1967,
Pubmed
Brinkley,
Managing the centrosome numbers game: from chaos to stability in cancer cell division.
2001,
Pubmed
Collins,
Centrosome biogenesis continues in the absence of microtubules during prolonged S-phase arrest.
2010,
Pubmed
Crasta,
DNA breaks and chromosome pulverization from errors in mitosis.
2012,
Pubmed
D'Assoro,
Centrosome amplification and the development of cancer.
2002,
Pubmed
Debec,
Centrioles: active players or passengers during mitosis?
2010,
Pubmed
Dippell,
The development of basal bodies in paramecium.
1968,
Pubmed
Dippell,
Effects of nuclease and protease digestion on the ultrastructure of Paramecium basal bodies.
1976,
Pubmed
Duensing,
Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins.
2009,
Pubmed
Friedländer,
The spindle as a basal body distributor. A study in the meiosis of the male silkworm moth, Bombyx mori.
1970,
Pubmed
Fu,
Structured illumination of the interface between centriole and peri-centriolar material.
2012,
Pubmed
Fuller,
The core of the mammalian centriole contains gamma-tubulin.
1995,
Pubmed
Ganem,
A mechanism linking extra centrosomes to chromosomal instability.
2009,
Pubmed
Gard,
Centrosome duplication continues in cycloheximide-treated Xenopus blastulae in the absence of a detectable cell cycle.
1990,
Pubmed
Goepfert,
Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis.
2002,
Pubmed
Gould,
The basal bodies of Chlamydomonas reinhardtii. Formation from probasal bodies, isolation, and partial characterization.
1975,
Pubmed
Gould,
The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation.
1977,
Pubmed
Guichard,
Procentriole assembly revealed by cryo-electron tomography.
2010,
Pubmed
Habedanck,
The Polo kinase Plk4 functions in centriole duplication.
2005,
Pubmed
Hall,
Basal body/centriolar DNA: molecular genetic studies in Chlamydomonas.
1989,
Pubmed
Hamaguchi,
Aster formation in sand dollar eggs by microinjection of calcium buffers and centriolar complexes isolated from starfish sperm.
1982,
Pubmed
,
Echinobase
Heald,
Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts.
1996,
Pubmed
Heidemann,
Aster formation in eggs of Xenopus laevis. Induction by isolated basal bodies.
1975,
Pubmed
Hornick,
Amphiastral mitotic spindle assembly in vertebrate cells lacking centrosomes.
2011,
Pubmed
Johnson,
Basal bodies and DNA.
1991,
Pubmed
Kallenbach,
Origin and maturation of centrioles in association with the nuclear envelope in hypertonic-stressed sea urchin eggs.
1982,
Pubmed
,
Echinobase
Karsenti,
Interconversion of metaphase and interphase microtubule arrays, as studied by the injection of centrosomes and nuclei into Xenopus eggs.
1984,
Pubmed
Keryer,
Centriole distribution during tripolar mitosis in Chinese hamster ovary cells.
1984,
Pubmed
Khodjakov,
Centrosome-independent mitotic spindle formation in vertebrates.
2000,
Pubmed
Kleylein-Sohn,
Plk4-induced centriole biogenesis in human cells.
2007,
Pubmed
La Terra,
The de novo centriole assembly pathway in HeLa cells: cell cycle progression and centriole assembly/maturation.
2005,
Pubmed
Lengauer,
Genetic instabilities in human cancers.
1998,
Pubmed
Loncarek,
Control of daughter centriole formation by the pericentriolar material.
2008,
Pubmed
MAZIA,
SH compounds in mitosis. II. The effect of mercaptoethanol on the structure of the mitotic apparatus in sea urchin eggs.
1958,
Pubmed
,
Echinobase
Maderspacher,
Theodor Boveri and the natural experiment.
2008,
Pubmed
,
Echinobase
Maller,
Spindle formation and cleavage in Xenopus eggs injected with centriole-containing fractions from sperm.
1976,
Pubmed
Marshall,
Centrioles take center stage.
2001,
Pubmed
Marshall,
Are there nucleic acids in the centrosome?
2000,
Pubmed
Mazia,
Centrosomes and mitotic poles.
1984,
Pubmed
Mazia,
The chromosome cycle and the centrosome cycle in the mitotic cycle.
1987,
Pubmed
Mazia,
The Multiplicity of the Mitotic Centers and the Time-Course of Their Duplication and Separation.
1960,
Pubmed
,
Echinobase
Mennella,
Amorphous no more: subdiffraction view of the pericentriolar material architecture.
2014,
Pubmed
Mennella,
Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization.
2012,
Pubmed
Nigg,
Centrosome aberrations: cause or consequence of cancer progression?
2002,
Pubmed
Orr-Weaver,
A checkpoint on the road to cancer.
1998,
Pubmed
Peel,
Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.
2007,
Pubmed
Pierre Mignot,
Basal-body-associated macromolecules: a continuing debate.
1993,
Pubmed
Rodrigues-Martins,
Revisiting the role of the mother centriole in centriole biogenesis.
2007,
Pubmed
Sapp,
Freewheeling centrioles.
1998,
Pubmed
Sir,
Loss of centrioles causes chromosomal instability in vertebrate somatic cells.
2013,
Pubmed
Sluder,
Experimental separation of pronuclei in fertilized sea urchin eggs: chromosomes do not organize a spindle in the absence of centrosomes.
1985,
Pubmed
,
Echinobase
Sluder,
Centriole number and the reproductive capacity of spindle poles.
1985,
Pubmed
,
Echinobase
Sluder,
Reproductive capacity of sea urchin centrosomes without centrioles.
1989,
Pubmed
,
Echinobase
Sluder,
Protein synthesis and the cell cycle: centrosome reproduction in sea urchin eggs is not under translational control.
1990,
Pubmed
,
Echinobase
Sluder,
Experimental analysis of the reproduction of spindle poles.
1985,
Pubmed
,
Echinobase
Sonnen,
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.
2012,
Pubmed
Steffen,
Aster-free spindle poles in insect spermatocytes: evidence for chromosome-induced spindle formation?
1986,
Pubmed
Strnad,
Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle.
2007,
Pubmed
Szöllösi,
A centriole-free Drosophila cell line. A high voltage EM study.
1986,
Pubmed
Uetake,
Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells.
2007,
Pubmed
Walczak,
A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.
1998,
Pubmed