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ECB-ART-42633
Molecules 2012 Nov 05;1711:13175-82. doi: 10.3390/molecules171113175.
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Spiculisporic acids B–D, three new γ-butenolide derivatives from a sea urchin-derived fungus Aspergillus sp. HDf2.

Wang R , Liu TM , Shen MH , Yang MQ , Feng QY , Tang XM , Li XM .


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Three new γ-butenolide derivatives 1–3, named spiculisporic acids B–D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1–3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell lines (SGC-7901, human gastric adenocarcinoma and SPC-A-1, human lung adenocarcinoma) and inhibitory activities against Staphylococcus aureus ATCC 51650 were investigated.

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Genes referenced: LOC100887844 LOC100893907 LOC115919910


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References [+] :
Blunt, Marine natural products. 2011, Pubmed