Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Biophys J
2011 Jun 22;10012:3008-15. doi: 10.1016/j.bpj.2011.04.052.
Show Gene links
Show Anatomy links
Viscoelastic properties of isolated collagen fibrils.
Shen ZL
,
Kahn H
,
Ballarini R
,
Eppell SJ
.
???displayArticle.abstract???
Understanding the viscoelastic behavior of collagenous tissues with complex hierarchical structures requires knowledge of the properties at each structural level. Whole tissues have been studied extensively, but less is known about the mechanical behavior at the submicron, fibrillar level. Using a microelectromechanical systems platform, in vitro coupled creep and stress relaxation tests were performed on collagen fibrils isolated from the sea cucumber dermis. Stress-strain-time data indicate that isolated fibrils exhibit viscoelastic behavior that could be fitted using the Maxwell-Weichert model. The fibrils showed an elastic modulus of 123 ± 46 MPa. The time-dependent behavior was well fit using the two-time-constant Maxwell-Weichert model with a fast time response of 7 ± 2 s and a slow time response of 102 ± 5 s. The fibrillar relaxation time was smaller than literature values for tissue-level relaxation time, suggesting that tissue relaxation is dominated by noncollagenous components (e.g., proteoglycans). Each specimen was tested three times, and the only statistically significant difference found was that the elastic modulus is larger in the first test than in the subsequent two tests, indicating that viscous properties of collagen fibrils are not sensitive to the history of previous tests.
Abramowitch,
An improved method to analyze the stress relaxation of ligaments following a finite ramp time based on the quasi-linear viscoelastic theory.
2004, Pubmed
Abramowitch,
An improved method to analyze the stress relaxation of ligaments following a finite ramp time based on the quasi-linear viscoelastic theory.
2004,
Pubmed
Asundi,
In vitro system for applying cyclic loads to connective tissues under displacement or force control.
2007,
Pubmed
Ciarletta,
A novel microstructural approach in tendon viscoelastic modelling at the fibrillar level.
2006,
Pubmed
Egan,
A constitutive model for the mechanical behaviour of soft connective tissues.
1987,
Pubmed
Eppell,
Nano measurements with micro-devices: mechanical properties of hydrated collagen fibrils.
2006,
Pubmed
Fung,
Elasticity of soft tissues in simple elongation.
1967,
Pubmed
Gautieri,
Deformation rate controls elasticity and unfolding pathway of single tropocollagen molecules.
2009,
Pubmed
Gautieri,
Hierarchical structure and nanomechanics of collagen microfibrils from the atomistic scale up.
2011,
Pubmed
Graham,
Structural changes in human type I collagen fibrils investigated by force spectroscopy.
2004,
Pubmed
Grant,
Tuning the elastic modulus of hydrated collagen fibrils.
2009,
Pubmed
Grashow,
Planar biaxial creep and stress relaxation of the mitral valve anterior leaflet.
2006,
Pubmed
Haut,
A constitutive equation for collagen fibers.
1972,
Pubmed
Heim,
Low strain nanomechanics of collagen fibrils.
2007,
Pubmed
Huang,
The role of flow-independent viscoelasticity in the biphasic tensile and compressive responses of articular cartilage.
2001,
Pubmed
Johnson,
A single integral finite strain viscoelastic model of ligaments and tendons.
1996,
Pubmed
Johnson,
Tensile and viscoelastic properties of human patellar tendon.
1994,
Pubmed
Kwan,
On the viscoelastic properties of the anteromedial bundle of the anterior cruciate ligament.
1993,
Pubmed
Lam,
Changes in the cyclic and static relaxations of the rabbit medial collateral ligament complex during maturation.
1993,
Pubmed
Leikin,
Direct measurement of forces between self-assembled proteins: temperature-dependent exponential forces between collagen triple helices.
1994,
Pubmed
Leikin,
Raman spectral evidence for hydration forces between collagen triple helices.
1997,
Pubmed
Liao,
The relation between collagen fibril kinematics and mechanical properties in the mitral valve anterior leaflet.
2007,
Pubmed
Nekouzadeh,
A simplified approach to quasi-linear viscoelastic modeling.
2007,
Pubmed
Provenzano,
Nonlinear ligament viscoelasticity.
2001,
Pubmed
Purslow,
Collagen orientation and molecular spacing during creep and stress-relaxation in soft connective tissues.
1998,
Pubmed
Puxkandl,
Viscoelastic properties of collagen: synchrotron radiation investigations and structural model.
2002,
Pubmed
Rigby,
The Mechanical Properties of Rat Tail Tendon.
1959,
Pubmed
Sarver,
Methods for quasi-linear viscoelastic modeling of soft tissue: application to incremental stress-relaxation experiments.
2003,
Pubmed
Sasaki,
Time-resolved X-ray diffraction from tendon collagen during creep using synchrotron radiation.
1999,
Pubmed
Sasaki,
Stress relaxation function of bone and bone collagen.
1993,
Pubmed
Schatzmann,
Effect of cyclic preconditioning on the tensile properties of human quadriceps tendons and patellar ligaments.
1998,
Pubmed
Screen,
Investigating load relaxation mechanics in tendon.
2008,
Pubmed
Shen,
Stress-strain experiments on individual collagen fibrils.
2008,
Pubmed
,
Echinobase
Shen,
In vitro fracture testing of submicron diameter collagen fibril specimens.
2010,
Pubmed
,
Echinobase
Silver,
Collagen self-assembly and the development of tendon mechanical properties.
2003,
Pubmed
Stella,
Time-dependent biaxial mechanical behavior of the aortic heart valve leaflet.
2007,
Pubmed
Svensson,
Viscoelastic behavior of discrete human collagen fibrils.
2010,
Pubmed
Wang,
Creep rupture of wallaby tail tendons.
1995,
Pubmed
Wenger,
Mechanical properties of collagen fibrils.
2007,
Pubmed
Woo,
Mathematical modeling of ligaments and tendons.
1993,
Pubmed
Woo,
The time and history-dependent viscoelastic properties of the canine medical collateral ligament.
1981,
Pubmed
Woo,
Mechanical properties of tendons and ligaments. I. Quasi-static and nonlinear viscoelastic properties.
1982,
Pubmed
Wren,
Effects of creep and cyclic loading on the mechanical properties and failure of human Achilles tendons.
2003,
Pubmed
Wu,
Quantitative constitutive behaviour and viscoelastic properties of fresh flexor tendons.
2006,
Pubmed
Yamamoto,
Mechanical properties of collagen fascicles from the rabbit patellar tendon.
1999,
Pubmed
Yang,
Mechanical properties of native and cross-linked type I collagen fibrils.
2008,
Pubmed
Yang,
Micromechanical bending of single collagen fibrils using atomic force microscopy.
2007,
Pubmed
van der Rijt,
Micromechanical testing of individual collagen fibrils.
2006,
Pubmed
