ECB-ART-41875
Chem Pharm Bull (Tokyo)
2011 Jan 01;591:106-8. doi: 10.1248/cpb.59.106.
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New diketopiperazine derivatives isolated from sea urchin-derived bacillus sp.
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Two new diketopiperazine derivatives, bacillusamides A (1) and B (2), have been isolated from the EtOAc extract of the sea urchin-derived Bacillus sp. along with the known cyclo(-L-pro-L-val-) (3), cyclo(-L-pro-L-tyr-) (4), cyclo(-L-pro-L-phe-) (5). These structures were elucidated by extensive spectroscopic methods. Furthermore, the absolute configurations of the amino acid residues were determined using Marfey''s method. Compound 1 displayed weak antifungal activity against Aspergillus niger.
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Genes referenced: LOC100887844 pus1