ECB-ART-40617
ACS Chem Biol
2008 Feb 15;32:84-6. doi: 10.1021/cb8000217.
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Ciliogenesis, ciliary function, and selective isolation.
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In addition to their classic role in cell motility, certain cilia have sensory or signaling functions. In sea urchin embryos, short motile cilia randomly propel the early embryo, while a group of long, immotile cilia appear later, coincident with directional swimming and localized within a region that gives rise to the larval nervous system. Motile cilia can be selectively removed by treatment with a novel derivative of dillapiol, leaving the putative sensory cilia for comparative investigation and a gently deciliated embryo ready for studies of regeneration signaling.
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Genes referenced: LOC100887844 LOC115919910