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Org Biomol Chem
2007 Feb 07;53:441-3. doi: 10.1039/b617344f.
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Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+).
Parkesh R
,
Vasudevan SR
,
Berry A
,
Galione A
,
Dowden J
,
Churchill GC
.
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A chemo-enzymatic synthesis of novel caged NAADP+ without the formation of multiple cage compounds has been achieved. The biological activity of the caged NAADP+ was demonstrated by its fast uncaging in intact sea-urchin eggs.
Bak,
NAADP receptors are present and functional in the heart.
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Bak,
NAADP receptors are present and functional in the heart.
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Cancela,
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells.
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Churchill,
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs.
2002,
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Cohen,
Caged NADP and NAD. Synthesis and characterization of functionally distinct caged compounds.
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Galione,
The NAADP receptor: new receptors or new regulation?
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Gee,
Characterization and application of photogeneration of calcium mobilizers cADP-ribose and nicotinic acid adenine dinucleotide phosphate from caged analogs.
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Hirayama,
Design, synthesis and photochemical properties of caged bile acids.
2003,
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Kantevari,
Synthesis and two-photon photolysis of 6-(ortho-nitroveratryl)-caged IP3 in living cells.
2006,
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Lee,
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose.
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Lee,
Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP.
1997,
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Lee,
Caged nicotinic acid adenine dinucleotide phosphate. Synthesis and use.
1997,
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Patel,
Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate, in the brain.
2000,
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