Ecotoxicol Environ Saf 2006 Oct 01;652:188-200. doi: 10.1016/j.ecoenv.2005.07.008.

Levels and effects of PCDD/Fs and co-PCBs in sediments, mussels, and sea stars of the intertidal zone in the southern North Sea and the English Channel.

???displayArticle.abstract???
There is considerable concern regarding dioxin-like compounds (DLCs) in the marine environment. These ubiquitous contaminants are highly resistant to degradation, highly accumulated by marine organisms, and extremely toxic. Concentrations of DLCs, including 7 polychlorodibenzo-p-dioxins, 10 polychlorodibenzofurans, and 4 coplanar polychlorinated biphenyls, were determined in sediments, mussels (Mytilus edulis), and sea stars (Asterias rubens) from five intertidal stations distributed along the Belgian coast and the English Channel. The induction of a biomarker, cytochrome P450 immunopositive protein (CYP1A IPP), was also measured in sea star pyloric caeca. Although no significant differences were found between the considered stations, DLC levels were found to be relatively high in biota, especially when the toxicity of these compounds is considered. Particular concern arises from TEQ values determined in mussels from all locations. Sea stars were found to be more discriminant between the stations. CYP1A IPP induction was found to be significantly related to DLC levels measured in sea stars and allowed significant discrimination between the considered stations.

???displayArticle.pubmedLink??? 16125238
???displayArticle.link??? Ecotoxicol Environ Saf


Genes referenced: inpp1 LOC100887844 LOC115917891