Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-38076
Traffic 2003 Jun 01;46:367-75. doi: 10.1034/j.1600-0854.2003.00099.x.
Show Gene links Show Anatomy links

Unconventional motoring: an overview of the Kin C and Kin I kinesins.

Ovechkina Y , Wordeman L .


???displayArticle.abstract???
All kinesins share a conserved core motor domain implying a common mechanism for generating force from ATP hydrolysis. How is it then that kinesins exhibit such divergent activities: motility, microtubule cross-linking and microtubule depolymerization? Although conventional motile kinesins have served as the paradigm for understanding kinesin function, the unconventional kinesins exploit variations on the motile theme to perform unexpected tasks. This review summarizes the biological functions and examines the possible molecular mechanisms of Kin C and Kin I unconventional kinesins. We also discuss the possible differences between the microtubule destabilization models proposed for Kar3 and Kin I kinesins.

???displayArticle.pubmedLink??? 12753646
???displayArticle.link??? Traffic
???displayArticle.grants??? [+]

Genes referenced: kin