Dev Genet 1999 Jan 01;252:83-6. doi: 10.1002/(SICI)1520-6408(1999)25:2<83::AID-DVG1>3.0.CO;2-J.

Fertilization in animals.

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Fertilization in mammalian and nonmammalian organisms has many features in common. These features include a final maturation phase for sperm and eggs, species-specific binding of sperm to eggs, penetration by sperm of one or more extracellular coats surrounding eggs, fusion of sperm and eggs, and activation of eggs. Implicit in this are a variety of basic molecular events, including receptor-ligand interactions, signalling cascades, specific proteolysis, and nuclear transformations. Here, several of these events are addressed for fertilization in animals as diverse as starfish and mice.

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