Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
The soluble sperm factor that causes Ca2+ release from sea-urchin (Lytechinus pictus) egg homogenates also triggers Ca2+ oscillations after injection into mouse eggs.
Parrington J
,
Jones KT
,
Lai A
,
Swann K
.
???displayArticle.abstract??? Cytosolic extracts of boar sperm contain a soluble phospholipase C (PLC) activity that induces Ca2+ release in sea-urchin (Lytechinus pictus) egg homogenates and an uncharacterized protein factor that causes Ca2+ oscillations when injected into mammalian eggs. In the present study we fractionated boar sperm extracts on three different FPLC chromatographic columns and found that the fractions that caused maximal Ca2+ release in sea-urchin egg homogenates were also the ones that triggered Ca2+ oscillations in mouse eggs. Our data suggests that the sperm factor which triggers Ca2+ oscillations in eggs contains a PLC and not the 33 kDa glucosamine deaminase previously suggested to be one its components.
Caramelli,
Nuclear phosphoinositide-specific phospholipase C, phosphatidylinositol 4,5-bisphosphate and protein kinase C during rat spermatogenesis.
1996, Pubmed
Caramelli,
Nuclear phosphoinositide-specific phospholipase C, phosphatidylinositol 4,5-bisphosphate and protein kinase C during rat spermatogenesis.
1996,
Pubmed
Ciapa,
Polyphosphoinositide metabolism during the fertilization wave in sea urchin eggs.
1992,
Pubmed
,
Echinobase
Clapper,
Inositol trisphosphate induces calcium release from nonmitochondrial stores i sea urchin egg homogenates.
1985,
Pubmed
,
Echinobase
Dupont,
Phospholipase C in mouse oocytes: characterization of beta and gamma isoforms and their possible involvement in sperm-induced Ca2+ spiking.
1996,
Pubmed
Fissore,
Activation of development in mammals: is there a role for a sperm cytosolic factor?
1998,
Pubmed
Galione,
A cytosolic sperm protein factor mobilizes Ca2+ from intracellular stores by activating multiple Ca2+ release mechanisms independently of low molecular weight messengers.
1997,
Pubmed
,
Echinobase
Homa,
A cytosolic sperm factor triggers calcium oscillations and membrane hyperpolarizations in human oocytes.
1994,
Pubmed
Jaffe,
Sources of calcium in egg activation: a review and hypothesis.
1983,
Pubmed
,
Echinobase
Jaffe,
First messengers at fertilization.
1990,
Pubmed
,
Echinobase
Jones,
The passage of Ca2+ and fluorescent markers between the sperm and egg after fusion in the mouse.
1998,
Pubmed
Jones,
A mammalian sperm cytosolic phospholipase C activity generates inositol trisphosphate and causes Ca2+ release in sea urchin egg homogenates.
1998,
Pubmed
,
Echinobase
Kyozuka,
Injection of sperm extract mimics spatiotemporal dynamics of Ca2+ responses and progression of meiosis at fertilization of ascidian oocytes.
1998,
Pubmed
Lawrence,
The effects of a Ca2+ chelator and heavy-metal-ion chelators upon Ca2+ oscillations and activation at fertilization in mouse eggs suggest a role for repetitive Ca2+ increases.
1998,
Pubmed
Lee,
The calcium transient in sea urchin eggs during fertilization requires the production of inositol 1,4,5-trisphosphate.
1998,
Pubmed
,
Echinobase
Mehlmann,
SH2 domain-mediated activation of phospholipase Cgamma is not required to initiate Ca2+ release at fertilization of mouse eggs.
1998,
Pubmed
Miyazaki,
Essential role of the inositol 1,4,5-trisphosphate receptor/Ca2+ release channel in Ca2+ waves and Ca2+ oscillations at fertilization of mammalian eggs.
1993,
Pubmed
,
Echinobase
Nakano,
Spatiotemporal dynamics of intracellular calcium in the mouse egg injected with a spermatozoon.
1997,
Pubmed
Parrington,
Calcium oscillations in mammalian eggs triggered by a soluble sperm protein.
1996,
Pubmed
Ribbes,
Phospholipase C from human sperm specific for phosphoinositides.
1987,
Pubmed
Sette,
Parthenogenetic activation of mouse eggs by microinjection of a truncated c-kit tyrosine kinase present in spermatozoa.
1997,
Pubmed
Shevchenko,
The human glucosamine-6-phosphate deaminase gene: cDNA cloning and expression, genomic organization and chromosomal localization.
1998,
Pubmed
Snow,
Fertilization stimulates an increase in inositol trisphosphate and inositol lipid levels in Xenopus eggs.
1996,
Pubmed
Stice,
Activation of mammalian oocytes by a factor obtained from rabbit sperm.
1990,
Pubmed
Stricker,
Intracellular injections of a soluble sperm factor trigger calcium oscillations and meiotic maturation in unfertilized oocytes of a marine worm.
1997,
Pubmed
Swann,
A cytosolic sperm factor stimulates repetitive calcium increases and mimics fertilization in hamster eggs.
1990,
Pubmed
Swann,
Different triggers for calcium oscillations in mouse eggs involve a ryanodine-sensitive calcium store.
1992,
Pubmed
Swann,
Ca2+ oscillations and sensitization of Ca2+ release in unfertilized mouse eggs injected with a sperm factor.
1994,
Pubmed
Tomes,
Activation of mouse sperm phosphatidylinositol-4,5 bisphosphate-phospholipase C by zona pellucida is modulated by tyrosine phosphorylation.
1996,
Pubmed
Turner,
Fertilization increases the polyphosphoinositide content of sea urchin eggs.
1984,
Pubmed
,
Echinobase
Vanha-Perttula,
Purification and characterization of phosphatidylinositol-specific phospholipase C from bovine spermatozoa.
1989,
Pubmed
Wolosker,
Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity.
1998,
Pubmed
Wu,
Injection of a porcine sperm factor triggers calcium oscillations in mouse oocytes and bovine eggs.
1997,
Pubmed
Wu,
Partial characterization of the calcium-releasing activity of porcine sperm cytosolic extracts.
1998,
Pubmed
