ECB-ART-37137
Ross Fiziol Zh Im I M Sechenova
1998 Oct 01;8410:1038-48.
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[Cholinergic receptors in early (pre-nervous) sea urchin embryos].
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Agonists of nicotinic acetylcholine receptors (nAChR) nicotine and 1-acetyl-4-methylpiperazine do not act on the early sea urchin embryogenesis but evoke calcium shock in both oocytes and early embryos under certain conditions. Many nAChR ligands protect both oocytes and embryos against this shock. There seem to exist putative nAChR on the cell surface of the early sea urchin oocytes and early embryos. Pre-nervous acetylcholine seems to be functionally coupled via these receptors with the second messengers, endogenous activators of the protein kinase C.
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Genes referenced: LOC100887844 LOC115919910 LOC576539 LOC586799 LOC590297 pkcl2