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Plant Physiol
1999 Feb 01;1192:417-28. doi: 10.1104/pp.119.2.417.
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Cell-specific production and antimicrobial activity of naphthoquinones in roots of lithospermum erythrorhizon
Brigham LA
,
Michaels PJ
,
Flores HE
.
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Pigmented naphthoquinone derivatives of shikonin are produced at specific times and in specific cells of Lithospermum erythrorhizon roots. Normal pigment development is limited to root hairs and root border cells in hairy roots grown on "noninducing" medium, whereas induction of additional pigment production by abiotic (CuSO4) or biotic (fungal elicitor) factors increases the amount of total pigment, changes the ratios of derivatives produced, and initiates production of pigment de novo in epidermal cells. When the biological activity of these compounds was tested against soil-borne bacteria and fungi, a wide range of sensitivity was recorded. Acetyl-shikonin and beta-hydroxyisovaleryl-shikonin, the two most abundant derivatives in both Agrobacterium rhizogenes-transformed "hairy-root" cultures and greenhouse-grown plant roots, were the most biologically active of the seven compounds tested. Hyphae of the pathogenic fungi Rhizoctonia solani, Pythium aphanidermatum, and Nectria hematococca induced localized pigment production upon contact with the roots. Challenge by R. solani crude elicitor increased shikonin derivative production 30-fold. We have studied the regulation of this suite of related, differentially produced, differentially active compounds to understand their role(s) in plant defense at the cellular level in the rhizosphere.
Bago,
Nitrate depletion and pH changes induced by the extraradical mycelium of the arbuscular mycorrhizal fungus Glomus intraradices grown in monoxenic culture.
1996, Pubmed
Bago,
Nitrate depletion and pH changes induced by the extraradical mycelium of the arbuscular mycorrhizal fungus Glomus intraradices grown in monoxenic culture.
1996,
Pubmed
Bennett,
Secondary metabolites in plant defence mechanisms.
1994,
Pubmed
Brigham,
Root border cells as tools in plant cell studies.
1995,
Pubmed
Bécard,
Early events of vesicular-arbuscular mycorrhiza formation on Ri T-DNA transformed roots.
1988,
Pubmed
Chappell,
The Biochemistry and Molecular Biology of Isoprenoid Metabolism.
1995,
Pubmed
Dixon,
Stress-Induced Phenylpropanoid Metabolism.
1995,
Pubmed
Fujita,
Production of shikonin derivatives by cell suspension cultures of Lithospermum erythrorhizon. III. Comparison of shikonin derivatives of cultured cells and ko-shikon.
1983,
Pubmed
Fujita,
Production of shikonin derivatives by cell suspension cultures of Lithospermum erythrorhizon : I. Effects of nitrogen sources on the production of shikonin derivatives.
1981,
Pubmed
Fujita,
Production of shikonin derivatives by cell suspension cultures of Lithospermum erythrorhizon : II. A new Medium for the production of shikonin derivatives.
1981,
Pubmed
Fukui,
Induction of shikonin biosynthesis by endogenous polysaccharides in Lithospermum erythrorhizon cell suspension cultures.
1990,
Pubmed
Hauska,
Phylloquinone in photosystem I: are quinones the secondary electron acceptors in all types of photosynthetic reaction centers?
1988,
Pubmed
Hawes,
Function of root border cells in plant health: pioneers in the rhizosphere.
1998,
Pubmed
Herrmann,
The shikimate pathway as an entry to aromatic secondary metabolism.
1995,
Pubmed
Jackson,
Plant-Microbe Interactions: Life and Death at the Interface.
1996,
Pubmed
LURIA,
Hybridization between Escherichia coli and Shigella.
1957,
Pubmed
Osbourn,
Preformed Antimicrobial Compounds and Plant Defense against Fungal Attack.
1996,
Pubmed
Papageorgiou,
Wound healing properties of naphthaquinone pigments from Alkanna tinctoria.
1978,
Pubmed
Papageorgiou,
Naturally occurring isohexenylnaphthazarin pigments: a new class of drugs.
1980,
Pubmed
Rhodes,
Physiological roles for secondary metabolites in plants: some progress, many outstanding problems.
1994,
Pubmed
Tabata,
[Antimicrobial activity of Lithospermum erythrorhizon callus cultures (author's transl)].
1975,
Pubmed
Tanaka,
[Pharmacodynamic study on "Shiunko." I. Antibacterial effect of "Shiunko"].
1972,
Pubmed
Tsukada,
Intracellular Localization and Secretion of Naphthoquinone Pigments in Cell Cultures of Lithospermum erythrorhizon.
1984,
Pubmed
