Prog Cell Cycle Res 1995 Jan 01;1:255-63. doi: 10.1007/978-1-4615-1809-9_20.

G-protein-mediated signal transduction for meiosis reinitiation in starfish oocyte.

???displayArticle.abstract???
Starfish oocyte maturation is induced by 1-methyladenine. There were apparently two forms of 1-methyladenine receptor affected by GTP gamma S. Pertussis toxin ADP-ribosylated the 39-kDa alpha subunit of a G protein and inhibited maturation. Also, the G protein was ADP-ribosylated by cholera toxin only when 1-methyladenine was added. The purified G protein had an heterotrimeric structure consisting of 39 kDa alpha, 37 kDa beta, and 8 kDa gamma subunits. The deduced amino acid sequence of the cDNA of starfish G alpha was 89% identical to mammalian Gi-1 alpha. The purified starfish beta gamma-subunits induced maturation when they were microinjected into oocytes.

???displayArticle.pubmedLink??? 9552368
???displayArticle.link??? Prog Cell Cycle Res