ECB-ART-35945
Biochem Biophys Res Commun
1994 Jul 15;2021:556-61. doi: 10.1006/bbrc.1994.1964.
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Calcium binding properties of rabbit liver protein disulfide isomerase.
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We have characterized the Ca2+ binding properties of protein disulfide isomerase (PDI). It binds 19 mol Ca2+/mol protein with low affinity, which is reduced by increasing the ionic strength. Ca2+ induced conformational changes detected by UV difference spectroscopy. These Ca2+ binding properties resemble those of a sea urchin egg 58 kDa protein.
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Genes referenced: LOC100887844 p4hb