ECB-ART-35075
Immunol Lett
1983 Feb 01;62:107-8. doi: 10.1016/0165-2478(83)90090-1.
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Effect of in vivo inoculation of bacteria on the spontaneous cytotoxicity of axial organ cells from Asterias rubens.
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In vivo inoculation of heat-killed bacteria in the coelomic cavity of starfish induces an increase of spontaneous cytotoxicity developed by axial organ (an ancestral lymphoid organ) cells, phenomenon demonstrated by an in vitro [51Cr]-release assay. This observation corroborates the existence of a sophisticated immune system in the echinoderms, a first-rate model for phylogenic study of the immune response.
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