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Echinobase
ECB-ART-34790
J Muscle Res Cell Motil 1981 Mar 01;21:131-40. doi: 10.1007/bf00712064.
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Effects of AMPPNP and vanadate on the mechanochemical crossbridge cycle in flagella.

Okuno M , Brokaw CJ .


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The non-hydrolysable ATP analogue, beta,gamma-imido-adenosine-5''-triphosphate (AMPPNP, adenylilimidodiphosphate) does not reduce the stiffness of demembranated sea urchin sperm flagella measured in the rigor state in the absence of MgATP2- and does not cause relaxation of rigor bends. The competitive inhibitions provide further evidence that the dynein-tubulin crossbridge cycle in flagella is similar to the actin-myosin crossbridge cycle.

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Genes referenced: dnah3 LOC100887844 LOC590297 tubgcp2

References [+] :
Brokaw, CO2-inhibition of the amplitude of bending of triton-demembranated sea urcin sperm flagella. 1977, Pubmed, Echinobase