ECB-ART-34668
Exp Cell Res
1983 Apr 15;1451:226-30. doi: 10.1016/s0014-4827(83)80025-1.
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Changes in cGMP levels on meiosis reinitiation of starfish oocytes.
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An intracellular level of cGMP (but not cAMP) transiently decreased the reinitiation of oocyte maturation in the starfish, Asterias amurensis. Exogenously applied cGMP inhibited hormone-induced maturation. Methylxanthines inhibited oocyte maturation by suppressing the decrease in cGMP levels. These results suggest that a decrease in cGMP levels is a prerequisite for meiosis reinitiation of starfish oocytes.
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