ECB-ART-34550
Toxicon
1982 Jan 01;203:655-8. doi: 10.1016/0041-0101(82)90059-9.
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Effect of marine glycosides on adenosinetriphosphatase activity.
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Marine glycosides from the sea cucumbers Actinopyga agassizi, Holothuria atra, Bohadschia argus, Cucumaria fraudatrix, Astichopus multifidus and Thelenota ananas inhibit both Na+-K+ ATPase and Mg2+-ATPase of rat brain in vitro. The glycoside-cholesterol complex of these compounds does not influence ATPase activity. Asterosaponins from starfishes Linckia guildingi and Linckia laevigata possess a slight inhibiting effect. The triterpene glycosides from sea cucumbers are more powerful inhibitors than steroidal glycosides from starfishes.
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Genes referenced: LOC100887844 LOC581395